A Novel Ti3C2 Mxene - HAP clay based Scaffold Sensor for Cancer Diagnosis and Tissue Regeneration (RFT749)

Invention Summary

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The primary intention is to pioneer the development of an innovative 3D printed scaffold sensor incorporating Ti3C2Tx MXene/HAP clay-based nanocomposites, which can achieve real-time monitoring of the circulating process of cancer cells to cancerous tumors at the bone site, paving the way for advancements in cancer treatment and delaying metastases

Benefits

  • Excellent biocompatibility and large specific surface area make them ideal for integration into biological systems, particularly in the context of tissue engineering
  • Adjustable high levels of electro-conductibility and mechanical properties make them well-suited for the development of sensors and ink materials for 3D printing. 
  • Unique ion-rich surface for polymer interaction that can facilitate easy interaction with polymers to form functional nanocomposites. These are pivotal for creating electrically conductive scaffold sensors for real-time evaluation of tumor cell-bone interactions.
  • These sensors can offer real-time insights into the impact of tumors on osteogenesis, monitor responses to new drugs, and curtail tumor formation and cancer metastases.
  • Applications

    • Real-time capture and evaluation of the intricate process of cancer cells circulating to cancerous tumors at the bone site. 
    • Tumor formation control.
    • Improving cancer treatment and delaying metastases. 

    Patents

    This technology is the subject of US Issued Patent No. 8,709,394 and is available for licensing/partnering opportunities.

    Contact

    NDSU Research Foundation
    info(at)ndsurf(dot)org
    (701) 231-8173

    NDSURF Tech Key

    RFT, 749, RFT749

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